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Alveolar epithelial cell fate is maintained in a spatially restricted manner to promote lung regeneration after acute injury
Alveolar epithelial type 2 (AT2) cells integrate signals from multiple molecular pathways to proliferate and differentiate to drive regeneration of the lung alveolus. Utilizing in vivo genetic and ex vivo organoid models, we investigated the role of Fgfr2 signaling in AT2 cells across the lifespan a...
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| Veröffentlicht in: | Cell Rep |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8220578/ https://ncbi.nlm.nih.gov/pubmed/33979629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.109092 |
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