Dnmt1 is required for proximal-distal patterning of the lung endoderm and for restraining alveolar type 2 cell fate

Lung endoderm development occurs through a series of finely coordinated transcriptional processes that are regulated by epigenetic mechanisms. However, the role of DNA methylation in regulating lung endoderm development remains poorly understood. We demonstrate that DNA methyltransferase 1 (Dnmt1) i...

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Publicat a:Dev Biol
Autors principals: Liberti, Derek C., Zepp, Jarod A., Bartoni, Christina A., Liberti, Kyle H., Zhou, Su, Lu, Minmin, Morley, Michael P., Morrisey, Edward E.
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6822389/
https://ncbi.nlm.nih.gov/pubmed/31242446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2019.06.019
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