Synchronous effects of targeted mitochondrial complex I inhibitors on tumor and immune cells abrogate melanoma progression

Metabolic heterogeneity within the tumor microenvironment promotes cancer cell growth and immune suppression. We determined the impact of mitochondria-targeted complex I inhibitors (Mito-CI) in melanoma. Mito-CI decreased mitochondria complex I oxygen consumption, Akt-FOXO signaling, blocked cell cy...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:iScience
Main Authors: AbuEid, Mahmoud, McAllister, Donna M., McOlash, Laura, Harwig, Megan Cleland, Cheng, Gang, Drouillard, Donovan, Boyle, Kathleen A., Hardy, Micael, Zielonka, Jacek, Johnson, Bryon D., Hill, R. Blake, Kalyanaraman, Balaraman, Dwinell, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8220235/
https://ncbi.nlm.nih.gov/pubmed/34189432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102653
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados