Oncolytic H-1 parvovirus binds to sialic acid on laminins for cell attachment and entry

H-1 parvovirus (H-1PV) is a promising anticancer therapy. However, in-depth understanding of its life cycle, including the host cell factors needed for infectivity and oncolysis, is lacking. This understanding may guide the rational design of combination strategies, aid development of more effective...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Kulkarni, Amit, Ferreira, Tiago, Bretscher, Clemens, Grewenig, Annabel, El-Andaloussi, Nazim, Bonifati, Serena, Marttila, Tiina, Palissot, Valérie, Hossain, Jubayer A., Azuaje, Francisco, Miletic, Hrvoje, Ystaas, Lars A. R., Golebiewska, Anna, Niclou, Simone P., Roeth, Ralf, Niesler, Beate, Weiss, Amélie, Brino, Laurent, Marchini, Antonio
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2021
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8219832/
https://ncbi.nlm.nih.gov/pubmed/34158478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24034-7
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