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Generation of an Adenovirus-Parvovirus Chimera with Enhanced Oncolytic Potential
In this study, our goal was to generate a chimeric adenovirus-parvovirus (Ad-PV) vector that combines the high-titer and efficient gene transfer of adenovirus with the anticancer potential of rodent parvovirus. To this end, the entire oncolytic PV genome was inserted into a replication-defective E1-...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2012
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3457320/ https://ncbi.nlm.nih.gov/pubmed/22787235 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00848-12 |
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