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NRF2 Loss Accentuates Parkinsonian Pathology and Behavioral Dysfunction in Human α-Synuclein Overexpressing Mice

Nuclear factor (erythroid-derived 2)-like 2 (NRF2) is a central regulator of cellular stress responses and its transcriptional activation promotes multiple cellular defense and survival mechanisms. The loss of NRF2 has been shown to increase oxidative and proteotoxic stress, two key pathological fea...

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Detaylı Bibliyografya
Yayımlandı:Aging Dis
Asıl Yazarlar: Anandhan, Annadurai, Nguyen, Nhat, Syal, Arjun, Dreher, Luke A, Dodson, Matthew, Zhang, Donna D, Madhavan, Lalitha
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: JKL International LLC 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8219498/
https://ncbi.nlm.nih.gov/pubmed/34221542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14336/AD.2021.0511
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