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A549 in-silico 1.0: A first computational model to simulate cell cycle dependent ion current modulation in the human lung adenocarcinoma

Lung cancer is still a leading cause of death worldwide. In recent years, knowledge has been obtained of the mechanisms modulating ion channel kinetics and thus of cell bioelectric properties, which is promising for oncological biomarkers and targets. The complex interplay of channel expression and...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Langthaler, Sonja, Rienmüller, Theresa, Scheruebel, Susanne, Pelzmann, Brigitte, Shrestha, Niroj, Zorn-Pauly, Klaus, Schreibmayer, Wolfgang, Koff, Andrew, Baumgartner, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8219159/
https://ncbi.nlm.nih.gov/pubmed/34157016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1009091
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