HIV-1 Env-Dependent Cell Killing by Bifunctional Small-Molecule/Peptide Conjugates

A strategy has been established for the synthesis of a family of bifunctional HIV-1 inhibitor covalent conjugates with the potential to bind simultaneously to both the gp120 and gp41 subunits of the HIV-1 envelope glycoprotein trimeric complex (Env). One component of the conjugates is derived from B...

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Publicado no:ACS Chem Biol
Main Authors: Gaffney, Althea, Nangarlia, Aakansha, Ang, Charles G., Gossert, Steven, Rashad Ahmed, Adel Ahmed, Hossain, Md Alamgir, Abrams, Cameron F., Smith, Amos B., Chaiken, Irwin
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8218882/
https://ncbi.nlm.nih.gov/pubmed/33410670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00888
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