Safety, Tolerability, and Pharmacokinetics of NTM-1632, a Novel Mixture of Three Monoclonal Antibodies against Botulinum Toxin B

Botulism is a rare, life-threatening paralytic disease caused by Clostridium botulinum neurotoxin (BoNT). Available treatments, including an equine antitoxin and human immune globulin, are given postexposure and challenging to produce and administer. NTM-1632 is an equimolar mixture of 3 human IgG m...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Guptill, J. T., Raja, S. M., Juel, V. C., Walter, E. B., Cohen-Wolkowiez, M., Hill, H., Sendra, E., Hauser, B., Jackson, P., Swamy, G. K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2021
Soggetti:
Experimental Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8218613/
https://ncbi.nlm.nih.gov/pubmed/33875433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02329-20
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