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Pharmacokinetics of Human Recombinant Anti-Botulinum Toxin Antibodies in Rats

Botulinum neurotoxins (BoNT) are potential biothreat agents due to their high lethality, potency, and ease of distribution, thus the development of antitoxins is a high priority to the US government. This study examined pre-clinical pharmacokinetic studies in rats of four oligoclonal anti-BoNT mAb-b...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: Espinoza, Yero, Wong, David, Ahene, Ago, Der, Kenneth, Martinez, Zachary, Pham, John, Cobb, Ronald R., Farr-Jones, Shauna, Marks, James. D., Tomic, Milan T.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6628388/
https://ncbi.nlm.nih.gov/pubmed/31212950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins11060345
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