Identification of the MuRF1 Skeletal Muscle Ubiquitylome Through Quantitative Proteomics

MuRF1 (TRIM63) is a muscle-specific E3 ubiquitin ligase and component of the ubiquitin proteasome system. MuRF1 is transcriptionally upregulated under conditions that cause muscle loss, in both rodents and humans, and is a recognized marker of muscle atrophy. In this study, we used in vivo electropo...

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Detalhes bibliográficos
Publicado no:Function (Oxf)
Main Authors: Baehr, Leslie M, Hughes, David C, Lynch, Sarah A, Van Haver, Delphi, Maia, Teresa Mendes, Marshall, Andrea G, Radoshevich, Lilliana, Impens, Francis, Waddell, David S, Bodine, Sue C
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8218097/
https://ncbi.nlm.nih.gov/pubmed/34179788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/function/zqab029
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