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Skeletal muscle atrophy and the E3 ubiquitin ligases MuRF1 and MAFbx/atrogin-1

Muscle RING finger 1 (MuRF1) and muscle atrophy F-box (MAFbx)/atrogin-1 were identified more than 10 years ago as two muscle-specific E3 ubiquitin ligases that are increased transcriptionally in skeletal muscle under atrophy-inducing conditions, making them excellent markers of muscle atrophy. In th...

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Detalhes bibliográficos
Main Authors: Bodine, Sue C., Baehr, Leslie M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166716/
https://ncbi.nlm.nih.gov/pubmed/25096180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00204.2014
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