The glucocorticoid receptor and FOXO1 synergistically activate the skeletal muscle atrophy-associated MuRF1 gene

The muscle specific ubiquitin E3 ligase MuRF1 has been implicated as a key regulator of muscle atrophy under a variety of conditions, such as during synthetic glucocorticoid treatment. FOXO class transcription factors have been proposed as important regulators of MuRF1 expression, but its regulation...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Waddell, David S., Baehr, Leslie M., van den Brandt, Jens, Johnsen, Steven A., Reichardt, Holger M., Furlow, J. David, Bodine, Sue C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2008
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652500/
https://ncbi.nlm.nih.gov/pubmed/18612045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00646.2007
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