Genetic Alterations in Gliomas Remodel the Tumor Immune Microenvironment and Impact Immune-Mediated Therapies

High grade gliomas are malignant brain tumors that arise in the central nervous system, in patients of all ages. Currently, the standard of care, entailing surgery and chemo radiation, exhibits a survival rate of 14-17 months. Thus, there is an urgent need to develop new therapeutic strategies for t...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Oncol
Main Authors: Garcia-Fabiani, Maria B., Haase, Santiago, Comba, Andrea, Carney, Stephen, McClellan, Brandon, Banerjee, Kaushik, Alghamri, Mahmoud S., Syed, Faisal, Kadiyala, Padma, Nunez, Felipe J., Candolfi, Marianela, Asad, Antonela, Gonzalez, Nazareno, Aikins, Marisa E., Schwendeman, Anna, Moon, James J., Lowenstein, Pedro R., Castro, Maria G.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Oncology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8217836/
https://ncbi.nlm.nih.gov/pubmed/34168976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.631037
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