PDTM-20. THE HISTONE MUTATION H3.3-G34R ENCOUNTERED IN PEDIATRIC HIGH GRADE GLIOMA MODIFIES THE TUMOR IMMUNE MICROENVIRONMENT RENDERING IT MORE PERMISSIVE FOR IMMUNE MEDIATED THERAPIES

Pediatric high grade gliomas (pHGGs) have a median survival (MS) of 9–15 months and are the most common malignant brain tumors in children. No significant improvement in the MS of these patients has been registered in decades. Thus, a representative in vivo model to study these tumors is critical. R...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Neuro Oncol
Egile Nagusiak: B Garcia-Fabiani, Maria, Kadiyala, Padma, Haase, Santiago, Alghamri, Mahmoud, Comba, Andrea, Nunez, Felipe, Whalen, Matthew, Lowenstein, Pedro, Castro, Maria
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2019
Gaiak:
Pediatric Tumors
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847884/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.796
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