Genetic Alterations in Gliomas Remodel the Tumor Immune Microenvironment and Impact Immune-Mediated Therapies

High grade gliomas are malignant brain tumors that arise in the central nervous system, in patients of all ages. Currently, the standard of care, entailing surgery and chemo radiation, exhibits a survival rate of 14-17 months. Thus, there is an urgent need to develop new therapeutic strategies for t...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Garcia-Fabiani, Maria B., Haase, Santiago, Comba, Andrea, Carney, Stephen, McClellan, Brandon, Banerjee, Kaushik, Alghamri, Mahmoud S., Syed, Faisal, Kadiyala, Padma, Nunez, Felipe J., Candolfi, Marianela, Asad, Antonela, Gonzalez, Nazareno, Aikins, Marisa E., Schwendeman, Anna, Moon, James J., Lowenstein, Pedro R., Castro, Maria G.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8217836/
https://ncbi.nlm.nih.gov/pubmed/34168976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.631037
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