CB1R activation in nucleus accumbens core promotes stress-induced reinstatement of cocaine seeking by elevating extracellular glutamate in a drug-paired context

Preclinical models of stress-induced relapse to drug use have shown that the dysregulation of glutamatergic transmission within the nucleus accumbens (NA) contributes notably to the reinstatement of cocaine-seeking behavior in rodents. In this sense, there has been increasing interest in the cannabi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Guzman, Andrea S., Avalos, Maria P., De Giovanni, Laura N., Euliarte, Pia V., Sanchez, Marianela A., Mongi-Bragato, Bethania, Rigoni, Daiana, Bollati, Flavia A., Virgolini, Miriam B., Cancela, Liliana M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8217548/
https://ncbi.nlm.nih.gov/pubmed/34155271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-92389-4
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