Cocaine Administered into the Medial Prefrontal Cortex Reinstates Cocaine-Seeking Behavior by Increasing AMPA Receptor-Mediated Glutamate Transmission in the Nucleus Accumbens

One of the major determinants of reinstatement to cocaine use among human addicts is acute reexposure to the drug, which often precipitates cocaine craving and relapse. We used an animal model of cocaine relapse to determine the role of the glutamatergic pathway from the medial prefrontal cortex (mP...

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Gepubliceerd in:J Neurosci
Hoofdauteurs: Park, W.-K., Bari, A. A., Jey, A. R., Anderson, S. M., Spealman, R. D., Rowlett, J. K., Pierce, R. C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2002
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6758324/
https://ncbi.nlm.nih.gov/pubmed/11923456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-07-02916.2002
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