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Nucleus accumbens GLT-1a overexpression reduces glutamate efflux during reinstatement of cocaine-seeking but is not sufficient to attenuate reinstatement

Cocaine use disorder is a chronically relapsing disease without FDA-approved treatments. Using a rodent model of cocaine relapse, we and others have previously demonstrated that the beta-lactam antibiotic ceftriaxone attenuates cue- and cocaine-primed reinstatement of cocaine-seeking. Ceftriaxone re...

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Detalhes bibliográficos
Publicado no:Neuropharmacology
Main Authors: Logan, Carly, LaCrosse, Amber L., Knackstedt, Lori A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6383073/
https://ncbi.nlm.nih.gov/pubmed/29567092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2018.03.022
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