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Glutamate transporter GLT-1 mediates N-acetylcysteine inhibition of cocaine reinstatement
Both pre-clinical and clinical studies indicate that N-acetylcysteine (NAC) may be useful in treating relapse to addictive drug use. Cocaine self-administration in rats reduces both cystine-glutamate exchange and glutamate transport via GLT-1 in the nucleus accumbens, and NAC treatment normalizes th...
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| 發表在: | Addict Biol |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4437505/ https://ncbi.nlm.nih.gov/pubmed/24612076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12127 |
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