Gene Expression Profiles of Human Cerebral Organoids Identify PPAR Pathway and PKM2 as Key Markers for Oxygen-Glucose Deprivation and Reoxygenation

Ischemic stroke is one of the most common neurological diseases. However, the impact of ischemic stroke on human cerebral tissue remains largely unknown due to a lack of ischemic human brain samples. In this study, we applied cerebral organoids derived from human induced pluripotent stem cells to ev...

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Detaylı Bibliyografya
Yayımlandı:Front Cell Neurosci
Asıl Yazarlar: Iwasa, Naoki, Matsui, Takeshi K., Iguchi, Naohiko, Kinugawa, Kaoru, Morikawa, Naritaka, Sakaguchi, Yoshihiko M., Shiota, Tomo, Kobashigawa, Shinko, Nakanishi, Mari, Matsubayashi, Masaya, Nagata, Riko, Kikuchi, Sotaro, Tanaka, Tatsuhide, Eura, Nobuyuki, Kiriyama, Takao, Izumi, Tesseki, Saito, Kozue, Kataoka, Hiroshi, Saito, Yuichi, Kimura, Wataru, Wanaka, Akio, Nishimura, Yuhei, Mori, Eiichiro, Sugie, Kazuma
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2021
Konular:
Cellular Neuroscience
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8217463/
https://ncbi.nlm.nih.gov/pubmed/34168538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2021.605030
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