Gene Expression Profiles of Human Cerebral Organoids Identify PPAR Pathway and PKM2 as Key Markers for Oxygen-Glucose Deprivation and Reoxygenation

Ischemic stroke is one of the most common neurological diseases. However, the impact of ischemic stroke on human cerebral tissue remains largely unknown due to a lack of ischemic human brain samples. In this study, we applied cerebral organoids derived from human induced pluripotent stem cells to ev...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Front Cell Neurosci
Main Authors: Iwasa, Naoki, Matsui, Takeshi K., Iguchi, Naohiko, Kinugawa, Kaoru, Morikawa, Naritaka, Sakaguchi, Yoshihiko M., Shiota, Tomo, Kobashigawa, Shinko, Nakanishi, Mari, Matsubayashi, Masaya, Nagata, Riko, Kikuchi, Sotaro, Tanaka, Tatsuhide, Eura, Nobuyuki, Kiriyama, Takao, Izumi, Tesseki, Saito, Kozue, Kataoka, Hiroshi, Saito, Yuichi, Kimura, Wataru, Wanaka, Akio, Nishimura, Yuhei, Mori, Eiichiro, Sugie, Kazuma
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2021
נושאים:
Cellular Neuroscience
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC8217463/
https://ncbi.nlm.nih.gov/pubmed/34168538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2021.605030
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