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Cellular Antioxidant Mechanisms Control Immunoglobulin Light Chain-Mediated Proximal Tubule Injury

A major cause of morbidity and mortality in multiple myeloma is kidney injury from overproduction of monoclonal immunoglobulin light chains (FLC). FLC can induce damage through the production of hydrogen peroxide, which activates pro-inflammatory and pro-apoptotic pathways. The present study focused...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Ying, Kai er, Feng, Wenguang, Ying, Wei-Zhong, Sanders, Paul W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8217262/
https://ncbi.nlm.nih.gov/pubmed/33989758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2021.05.011
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