Amino terminus of cardiac myosin binding protein-C regulates cardiac contractility

Phosphorylation of cardiac myosin binding protein-C (cMyBP-C) regulates cardiac contraction through modulation of actomyosin interactions mediated by the protein’s amino terminal (N’)-region (C0-C2 domains, 358 amino acids). On the other hand, dephosphorylation of cMyBP-C during myocardial injury re...

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發表在:J Mol Cell Cardiol
Main Authors: Lynch, Thomas L., Kumar, Mohit, McNamara, James W., Kuster, Diederik W.D., Sivaguru, Mayandi, Singh, Rohit R., Previs, Michael J., Lee, Kyoung Hwan, Kuffel, Gina, Zilliox, Michael J., Lin, Brian Leei, Ma, Weikang, Gibson, Aaron M., Blaxall, Burns C., Nieman, Michelle L, Lorenz, John N., Leichter, Dana M., Leary, Owen P., Janssen, Paul M.L., de Tombe, Pieter P., Gilbert, Richard J., Craig, Roger, Irving, Thomas, Warshaw, David M., Sadayappan, Sakthivel
格式: Artigo
語言:Inglês
出版: 2021
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8217138/
https://ncbi.nlm.nih.gov/pubmed/33781820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2021.03.009
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