Altered C10 domain in cardiac myosin binding protein-C results in hypertrophic cardiomyopathy

AIMS: A 25-base pair deletion in the cardiac myosin binding protein-C (cMyBP-C) gene (MYBPC3), proposed to skip exon 33, modifies the C10 domain (cMyBP-C(ΔC10mut)) and is associated with hypertrophic cardiomyopathy (HCM) and heart failure, affecting approximately 100 million South Asians. However, t...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cardiovasc Res
Main Authors: Kuster, Diederik W D, Lynch, Thomas L, Barefield, David Y, Sivaguru, Mayandi, Kuffel, Gina, Zilliox, Michael J, Lee, Kyoung Hwan, Craig, Roger, Namakkal-Soorappan, Rajasekaran, Sadayappan, Sakthivel
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6872972/
https://ncbi.nlm.nih.gov/pubmed/31050699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvz111
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados