Amino terminus of cardiac myosin binding protein-C regulates cardiac contractility

Phosphorylation of cardiac myosin binding protein-C (cMyBP-C) regulates cardiac contraction through modulation of actomyosin interactions mediated by the protein’s amino terminal (N’)-region (C0-C2 domains, 358 amino acids). On the other hand, dephosphorylation of cMyBP-C during myocardial injury re...

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Publicat a:J Mol Cell Cardiol
Autors principals: Lynch, Thomas L., Kumar, Mohit, McNamara, James W., Kuster, Diederik W.D., Sivaguru, Mayandi, Singh, Rohit R., Previs, Michael J., Lee, Kyoung Hwan, Kuffel, Gina, Zilliox, Michael J., Lin, Brian Leei, Ma, Weikang, Gibson, Aaron M., Blaxall, Burns C., Nieman, Michelle L, Lorenz, John N., Leichter, Dana M., Leary, Owen P., Janssen, Paul M.L., de Tombe, Pieter P., Gilbert, Richard J., Craig, Roger, Irving, Thomas, Warshaw, David M., Sadayappan, Sakthivel
Format: Artigo
Idioma:Inglês
Publicat: 2021
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8217138/
https://ncbi.nlm.nih.gov/pubmed/33781820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2021.03.009
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