Amino terminus of cardiac myosin binding protein-C regulates cardiac contractility

Phosphorylation of cardiac myosin binding protein-C (cMyBP-C) regulates cardiac contraction through modulation of actomyosin interactions mediated by the protein’s amino terminal (N’)-region (C0-C2 domains, 358 amino acids). On the other hand, dephosphorylation of cMyBP-C during myocardial injury re...

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Bibliographic Details
Published in:J Mol Cell Cardiol
Main Authors: Lynch, Thomas L., Kumar, Mohit, McNamara, James W., Kuster, Diederik W.D., Sivaguru, Mayandi, Singh, Rohit R., Previs, Michael J., Lee, Kyoung Hwan, Kuffel, Gina, Zilliox, Michael J., Lin, Brian Leei, Ma, Weikang, Gibson, Aaron M., Blaxall, Burns C., Nieman, Michelle L, Lorenz, John N., Leichter, Dana M., Leary, Owen P., Janssen, Paul M.L., de Tombe, Pieter P., Gilbert, Richard J., Craig, Roger, Irving, Thomas, Warshaw, David M., Sadayappan, Sakthivel
Format: Artigo
Language:Inglês
Published: 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8217138/
https://ncbi.nlm.nih.gov/pubmed/33781820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2021.03.009
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