Combined Cell-free DNA and RNA Profiling of the Androgen Receptor: Clinical Utility of a Novel Multianalyte Liquid Biopsy Assay for Metastatic Prostate Cancer

BACKGROUND: The androgen receptor (AR) remains a critical driver in metastatic castration-resistant prostate cancer (mCRPC). Profiling AR aberrations in both circulating DNA and RNA may identify key predictive and/or prognostic biomarkers in the context of contemporary systemic therapy. OBJECTIVE: T...

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Vydáno v:Eur Urol
Hlavní autoři: Fettke, Heidi, Kwan, Edmond M., Docanto, Maria M., Bukczynska, Patricia, Ng, Nicole, Graham, Lisa-Jane K., Mahon, Kate, Hauser, Christine, Tan, Winston, Wang, Xiao Hong, Zhao, Zhixin, Zheng, Tiantian, Zhou, Kemin, Du, Pan, Yu, Jianjun, Huang, Yong, Jia, Shidong, Kohli, Manish, Horvath, Lisa G., Azad, Arun A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8216705/
https://ncbi.nlm.nih.gov/pubmed/32487321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eururo.2020.03.044
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