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Systemic CLIP-seq analysis and game theory approach to model microRNA mode of binding
microRNAs (miRNAs) associate with Ago proteins to post-transcriptionally silence gene expression by targeting mRNAs. To characterize the modes of miRNA-binding, we developed a novel computational framework, called optiCLIP, which considers the reproducibility of the identified peaks among replicates...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8216473/ https://ncbi.nlm.nih.gov/pubmed/33823551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab198 |
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