Post-transcriptional gene silencing mediated by microRNAs is controlled by nucleoplasmic Sfpq

There is a growing body of evidence about the presence and the activity of the miRISC in the nucleus of mammalian cells. Here, we show by quantitative proteomic analysis that Ago2 interacts with the nucleoplasmic protein Sfpq in an RNA-dependent fashion. By a combination of HITS-CLIP and transcripto...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Bottini, Silvia, Hamouda-Tekaya, Nedra, Mategot, Raphael, Zaragosi, Laure-Emmanuelle, Audebert, Stephane, Pisano, Sabrina, Grandjean, Valerie, Mauduit, Claire, Benahmed, Mohamed, Barbry, Pascal, Repetto, Emanuela, Trabucchi, Michele
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5662751/
https://ncbi.nlm.nih.gov/pubmed/29084942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01126-x
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