Post-transcriptional gene silencing mediated by microRNAs is controlled by nucleoplasmic Sfpq

There is a growing body of evidence about the presence and the activity of the miRISC in the nucleus of mammalian cells. Here, we show by quantitative proteomic analysis that Ago2 interacts with the nucleoplasmic protein Sfpq in an RNA-dependent fashion. By a combination of HITS-CLIP and transcripto...

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Библиографические подробности
Опубликовано в: :Nat Commun
Главные авторы: Bottini, Silvia, Hamouda-Tekaya, Nedra, Mategot, Raphael, Zaragosi, Laure-Emmanuelle, Audebert, Stephane, Pisano, Sabrina, Grandjean, Valerie, Mauduit, Claire, Benahmed, Mohamed, Barbry, Pascal, Repetto, Emanuela, Trabucchi, Michele
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2017
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5662751/
https://ncbi.nlm.nih.gov/pubmed/29084942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01126-x
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