The structure of the mouse ADAT2/ADAT3 complex reveals the molecular basis for mammalian tRNA wobble adenosine-to-inosine deamination

Post-transcriptional modification of tRNA wobble adenosine into inosine is crucial for decoding multiple mRNA codons by a single tRNA. The eukaryotic wobble adenosine-to-inosine modification is catalysed by the ADAT (ADAT2/ADAT3) complex that modifies up to eight tRNAs, requiring a full tRNA for act...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Ramos-Morales, Elizabeth, Bayam, Efil, Del-Pozo-Rodríguez, Jordi, Salinas-Giegé, Thalia, Marek, Martin, Tilly, Peggy, Wolff, Philippe, Troesch, Edouard, Ennifar, Eric, Drouard, Laurence, Godin, Juliette D, Romier, Christophe
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2021
Soggetti:
Structural Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8216470/
https://ncbi.nlm.nih.gov/pubmed/34057470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab436
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