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An adenosine-to-inosine tRNA-editing enzyme that can perform C-to-U deamination of DNA

Adenosine-to-inosine editing in the anticodon of tRNAs is essential for viability. Enzymes mediating tRNA adenosine deamination in bacteria and yeast contain cytidine deaminase-conserved motifs, suggesting an evolutionary link between the two reactions. In trypanosomatids, tRNAs undergo both cytidin...

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Detalhes bibliográficos
Main Authors: Rubio, Mary Anne T., Pastar, Irena, Gaston, Kirk W., Ragone, Frank L., Janzen, Christian J., Cross, George A. M., Papavasiliou, F. Nina, Alfonzo, Juan D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876531/
https://ncbi.nlm.nih.gov/pubmed/17483465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702394104
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