A Single Zinc Ion Is Sufficient for an Active Trypanosoma brucei tRNA Editing Deaminase

Editing of adenosine (A) to inosine (I) at the first anticodon position in tRNA is catalyzed by adenosine deaminases acting on tRNA (ADATs). This essential reaction in bacteria and eukarya permits a single tRNA to decode multiple codons. Bacterial ADATa is a homodimer with two bound essential Zn(2+)...

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Detalhes bibliográficos
Main Authors: Spears, Jessica L., Rubio, Mary Anne T., Gaston, Kirk W., Wywial, Ewa, Strikoudis, Alexandros, Bujnicki, Janusz M., Papavasiliou, F. Nina, Alfonzo, Juan D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121520/
https://ncbi.nlm.nih.gov/pubmed/21507956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.243568
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