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Unusual non-canonical intron editing important for tRNA splicing in Trypanosoma brucei

In cells, tRNAs are synthesized as precursor molecules bearing extra sequences at their 5′ and 3′ ends. Some tRNAs also contain introns which, in archaea and eukaryotes, are cleaved by an evolutionarily conserved endonuclease complex that generates fully functional mature tRNAs. In addition, tRNAs u...

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Detalhes bibliográficos
Main Authors: Rubio, Mary Anne T., Paris, Zdeněk, Gaston, Kirk W., Fleming, Ian M.C., Sample, Paul, Trotta, Christopher, Alfonzo, Juan D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3825838/
https://ncbi.nlm.nih.gov/pubmed/24095278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.08.042
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