The essential function of the Trypanosoma brucei Trl1 homolog in procyclic cells is maturation of the intron-containing tRNA(Tyr)

Trypanosoma brucei, the etiologic agent of sleeping sickness, encodes a single intron-containing tRNA, tRNA(Tyr), and splicing is essential for its viability. In Archaea and Eukarya, tRNA splicing requires a series of enzymatic steps that begin with intron cleavage by a tRNA-splicing endonuclease an...

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Publicado no:RNA
Main Authors: Lopes, Raphael R.S., Silveira, Gilbert de O., Eitler, Roberta, Vidal, Raphael S., Kessler, Alan, Hinger, Scott, Paris, Zdeněk, Alfonzo, Juan D., Polycarpo, Carla
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931112/
https://ncbi.nlm.nih.gov/pubmed/27284166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.056242.116
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