tRNA deamination by ADAT requires substrate-specific recognition mechanisms and can be inhibited by tRFs

Adenosine deaminase acting on transfer RNA (ADAT) is an essential eukaryotic enzyme that catalyzes the deamination of adenosine to inosine at the first position of tRNA anticodons. Mammalian ADATs modify eight different tRNAs, having increased their substrate range from a bacterial ancestor that lik...

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Detaylı Bibliyografya
Yayımlandı:RNA
Asıl Yazarlar: Roura Frigolé, Helena, Camacho, Noelia, Castellví Coma, Maria, Fernández-Lozano, Carla, García-Lema, Jorge, Rafels-Ybern, Àlbert, Canals, Albert, Coll, Miquel, Ribas de Pouplana, Lluís
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467012/
https://ncbi.nlm.nih.gov/pubmed/30737359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.068189.118
Etiketler: Etiketle
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