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Suppression of IgE-mediated anaphylaxis and food allergy with monovalent anti-FcεRIα monoclonal antibodies
BACKGROUND: Mast cell and basophil activation by antigen crosslinking of FcεRI-bound IgE is central to allergy pathogenesis. We previously demonstrated global suppression of this process by rapid desensitization with anti-FcεRIα mAbs. OBJECTIVE: Determine whether use of monovalent (mv) anti-FcεRIα m...
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| Pubblicato in: | J Allergy Clin Immunol |
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| Autori principali: | , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8215870/ https://ncbi.nlm.nih.gov/pubmed/33326804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2020.10.045 |
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