Rapid desensitization of humanized mice with anti-human FcεRIα monoclonal antibodies

BACKGROUND: Anaphylaxis is classically mediated by allergen crosslinking of IgE bound to the α chain of FcεRI, the mast cell/basophil high affinity IgE receptor. Allergen crosslinking of the IgE/FcεRI complex activates these cells, inducing release of disease-causing mediators, cytokines and enzymes...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:J Allergy Clin Immunol
Autores principales: Khodoun, Marat V., Morris, Suzanne C., Angerman, Elizabeth, Potter, Crystal, Schuman, Richard, Wunderlich, Mark, Maciag, Joseph J., Locker, Kathryn C. Sullivan, Mulloy, James C., Herr, Andrew B., Finkelman, Fred D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7607676/
https://ncbi.nlm.nih.gov/pubmed/31836406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2019.12.003
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares