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Rapid desensitization of humanized mice with anti-human FcεRIα monoclonal antibodies
BACKGROUND: Anaphylaxis is classically mediated by allergen crosslinking of IgE bound to the α chain of FcεRI, the mast cell/basophil high affinity IgE receptor. Allergen crosslinking of the IgE/FcεRI complex activates these cells, inducing release of disease-causing mediators, cytokines and enzymes...
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| Publicado en: | J Allergy Clin Immunol |
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| Autores principales: | , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7607676/ https://ncbi.nlm.nih.gov/pubmed/31836406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2019.12.003 |
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