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RAGE interacts with the necroptotic protein RIPK3 and mediates transfusion-induced danger signal release

RBC transfusion is associated with increased morbidity and mortality in critically ill patients. Endothelial cell necroptosis and subsequent damage-associated molecular pattern (DAMP) release has been identified as a mechanism of injury following RBC transfusion. Mounting evidence implicates the pro...

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Detalhes bibliográficos
Publicado no:Vox Sang
Main Authors: Faust, Hilary, Lam, LK Metthew, Hotz, Meghan J., Qing, Danielle, Mangalmurti, Nilam S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8215843/
https://ncbi.nlm.nih.gov/pubmed/32633835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/vox.12946
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