Systems pharmacogenomics identifies novel targets and clinically actionable therapeutics for medulloblastoma

BACKGROUND: Medulloblastoma (MB) is the most common malignant paediatric brain tumour and a leading cause of cancer-related mortality and morbidity. Existing treatment protocols are aggressive in nature resulting in significant neurological, intellectual and physical disabilities for the children un...

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Detalhes bibliográficos
Publicado no:Genome Med
Main Authors: Genovesi, Laura A., Millar, Amanda, Tolson, Elissa, Singleton, Matthew, Hassall, Emily, Kojic, Marija, Brighi, Caterina, Girard, Emily, Andradas, Clara, Kuchibhotla, Mani, Bhuva, Dharmesh D., Endersby, Raelene, Gottardo, Nicholas G., Bernard, Anne, Adolphe, Christelle, Olson, James M., Taylor, Michael D., Davis, Melissa J., Wainwright, Brandon J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8215804/
https://ncbi.nlm.nih.gov/pubmed/34154646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-021-00920-z
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