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MBRS-35. COMBINING Chk1/2 INHIBITION WITH RADIATION ENHANCES IN VITRO AND IN VIVO CYTOTOXICITY IN MEDULLOBLASTOMA
Medulloblastoma is a heterogeneous disease, comprising four molecular subgroups, termed WNT, SHH, Group 3 and Group 4. Each has distinct clinical, pathological, and molecular features. Surgical resection and craniospinal irradiation followed by chemotherapy are the mainstay of medulloblastoma treatm...
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| Udgivet i: | Neuro Oncol |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6012623/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.480 |
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