MBRS-35. COMBINING Chk1/2 INHIBITION WITH RADIATION ENHANCES IN VITRO AND IN VIVO CYTOTOXICITY IN MEDULLOBLASTOMA

Medulloblastoma is a heterogeneous disease, comprising four molecular subgroups, termed WNT, SHH, Group 3 and Group 4. Each has distinct clinical, pathological, and molecular features. Surgical resection and craniospinal irradiation followed by chemotherapy are the mainstay of medulloblastoma treatm...

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Publicat a:Neuro Oncol
Autors principals: Endersby, Raelene, Hii, Hilary, Strowger, Brooke, Dyer, Patrick, Howlett, Meegan, Kuchibhotla, Mani, Gottardo, Nicholas
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012623/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.480
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