Veliparib Is an Effective Radiosensitizing Agent in a Preclinical Model of Medulloblastoma

Medulloblastoma is the most common malignant childhood brain tumor, and 5-year overall survival rates are as low as 40% depending on molecular subtype, with new therapies critically important. As radiotherapy and chemotherapy act through the induction of DNA damage, the sensitization of cancer cells...

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Detalles Bibliográficos
Publicado en:Front Mol Biosci
Autores principales: Buck, Jessica, Dyer, Patrick J. C., Hii, Hilary, Carline, Brooke, Kuchibhotla, Mani, Byrne, Jacob, Howlett, Meegan, Whitehouse, Jacqueline, Ebert, Martin A., McDonald, Kerrie L., Gottardo, Nicholas G., Endersby, Raelene
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8116896/
https://ncbi.nlm.nih.gov/pubmed/33996894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.633344
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