USP1-dependent RPS16 protein stability drives growth and metastasis of human hepatocellular carcinoma cells

BACKGROUND: Hepatocellular carcinoma (HCC) remains a medical challenge due to its high proliferation and metastasis. Although deubiquitinating enzymes (DUBs) play a key role in regulating protein degradation, their pathological roles in HCC have not been fully elucidated. METHODS: By using biomass s...

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Veröffentlicht in:J Exp Clin Cancer Res
Hauptverfasser: Liao, Yuning, Shao, Zhenlong, Liu, Yuan, Xia, Xiaohong, Deng, Yuanfei, Yu, Cuifu, Sun, Wenshuang, Kong, Weiyao, He, Xiaoyue, Liu, Fang, Guo, Zhiqiang, Chen, Guoxing, Tang, Daolin, Gan, Huoye, Liu, Jinbao, Huang, Hongbiao
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8215741/
https://ncbi.nlm.nih.gov/pubmed/34154657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-02008-3
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