Growth arrest and apoptosis induction in androgen receptor-positive human breast cancer cells by inhibition of USP14-mediated androgen receptor deubiquitination

It has been well known that androgen receptor (AR) is critical to prostate cancer development and progression. It has also been documented that AR is expressed in more than 60% of breast tumors, which promotes the growth of estrogen receptor-negative (ER(–))/AR-positive (AR(+)) breast cancer cells....

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Liao, Yuning, Xia, Xiaohong, Liu, Ningning, Cai, Jianyu, Guo, Zhiqiang, Li, Yanling, Jiang, Lili, Dou, Q. Ping, Tang, Daolin, Huang, Hongbiao, Liu, Jinbao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886989/
https://ncbi.nlm.nih.gov/pubmed/29353883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-017-0069-z
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