Growth arrest and apoptosis induction in androgen receptor-positive human breast cancer cells by inhibition of USP14-mediated androgen receptor deubiquitination

It has been well known that androgen receptor (AR) is critical to prostate cancer development and progression. It has also been documented that AR is expressed in more than 60% of breast tumors, which promotes the growth of estrogen receptor-negative (ER(–))/AR-positive (AR(+)) breast cancer cells....

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Gepubliceerd in:Oncogene
Hoofdauteurs: Liao, Yuning, Xia, Xiaohong, Liu, Ningning, Cai, Jianyu, Guo, Zhiqiang, Li, Yanling, Jiang, Lili, Dou, Q. Ping, Tang, Daolin, Huang, Hongbiao, Liu, Jinbao
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5886989/
https://ncbi.nlm.nih.gov/pubmed/29353883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-017-0069-z
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