USP10 deletion inhibits macrophage-derived foam cell formation and cellular-oxidized low density lipoprotein uptake by promoting the degradation of CD36

Foam cell formation process is involved in the pathogenesis of atherosclerosis (AS). Activation of this biological process depends on lipid uptake by scavenger receptors, such as CD36, SR-A and SR-B1. Among these receptors, CD36 is the principal one because it dominates roughly 50% lipid uptake in m...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Xia, Xiaohong, Hu, Tumei, He, Jinchan, Xu, Qiong, Yu, Cuifu, Liu, Xiaolin, Shao, Zhenlong, Liao, Yuning, Huang, Hongbiao, Liu, Ningning
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7746336/
https://ncbi.nlm.nih.gov/pubmed/33197885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.104003
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