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Robustness of differential gene expression analysis of RNA-seq

RNA-sequencing (RNA-seq) is a relatively new technology that lacks standardisation. RNA-seq can be used for Differential Gene Expression (DGE) analysis, however, no consensus exists as to which methodology ensures robust and reproducible results. Indeed, it is broadly acknowledged that DGE methods p...

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Bibliografiske detaljer
Udgivet i:Comput Struct Biotechnol J
Main Authors: Stupnikov, A., McInerney, C.E., Savage, K.I., McIntosh, S.A., Emmert-Streib, F., Kennedy, R., Salto-Tellez, M., Prise, K.M., McArt, D.G.
Format: Artigo
Sprog:Inglês
Udgivet: Research Network of Computational and Structural Biotechnology 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8214188/
https://ncbi.nlm.nih.gov/pubmed/34188784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2021.05.040
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