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Examining lysyl oxidase-like modulation of collagen architecture in 3D spheroid models of idiopathic pulmonary fibrosis via second-harmonic generation microscopy

Significance: Idiopathic pulmonary fibrosis (IPF) patients have a poor prognosis with short lifespan following diagnosis as there are limited effective treatment options. Despite matrix stiffening being the hallmark of the disease there remains a lack of knowledge surrounding the underlying collagen...

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Detalhes bibliográficos
Publicado no:J Biomed Opt
Main Authors: James, Darian S., Brereton, Christopher J., Davies, Donna E., Jones, Mark G., Campagnola, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society of Photo-Optical Instrumentation Engineers 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8212879/
https://ncbi.nlm.nih.gov/pubmed/34145800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.JBO.26.6.066501
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