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Helenalin Facilitates Reactive Oxygen Species-Mediated Apoptosis and Cell Cycle Arrest by Targeting Thioredoxin Reductase-1 in Human Prostate Cancer Cells

BACKGROUND: Helenalin is a pseudoguaianolide natural product with anti-cancer activities. This study investigated the underlying mechanism of the anti-prostate cancer effects of helenalin in vitro. MATERIAL/METHODS: CCK-8 assay was performed to detect the optimal concentrations of helenalin in DU145...

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Dettagli Bibliografici
Pubblicato in:Med Sci Monit
Autori principali: Yang, Mei, Zhang, Weihua, Yu, Xiuxiu, Wang, Feng, Li, Yeping, Zhang, Yan, Yang, Yu
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Scientific Literature, Inc. 2021
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8212699/
https://ncbi.nlm.nih.gov/pubmed/34125740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.930083
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