A carregar...
Acetaminophen Reactive Intermediates Target Hepatic Thioredoxin Reductase
[Image: see text] Acetaminophen (APAP) is metabolized in the liver to N-acetyl-p-benzoquinone imine (NAPQI), an electrophilic metabolite known to bind liver proteins resulting in hepatotoxicity. Mammalian thioredoxin reductase (TrxR) is a cellular antioxidant containing selenocysteine (Sec) in its C...
Na minha lista:
| Main Authors: | , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2014
|
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4033643/ https://ncbi.nlm.nih.gov/pubmed/24661219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx5000443 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|